Cambridge is best known for the University of Cambridge, which includes the renowned Cavendish Laboratory, King's College Chapel, and the Cambridge University Library. The Cambridge skyline is dominated by the last two, along with the chimney of Addenbrooke's Hospital in the far south of the city and St John's College Chapel tower in the north. The city's name is pronounced /'keɪm.bɹɪdʒ/, as opposed to another Cambridge in Gloucestershire, England, which is pronounced /'kæm.bɹɪdʒ/.

According to the 2001 United Kingdom census, the City's population was 108,863 (including 22,153 students), and the population of the urban area (which includes parts of South Cambridgeshire district) is estimated to be 130,000.